:root{--navy:#102a35;--navy2:#173845;--ink:#1c3441;--muted:#667b82;--teal:#0a827b;--teal-soft:#e6f4f0;--paper:#f5f7f6;--white:#fff;--line:#dfe9e7;--amber:#a96b16;--amber-bg:#fff6e6;--red:#ad4341;--red-bg:#fff0eb;--shadow:0 12px 32px rgba(24,59,67,.055)}*{box-sizing:border-box}html{scroll-behavior:smooth}body{margin:0;background:var(--paper);color:var(--ink);font-family:'DM Sans',system-ui,-apple-system,sans-serif;font-size:14px;line-height:1.5}a{color:var(--teal);text-decoration:none}a:hover{text-decoration:underline}button,input,select,textarea{font:inherit}button{cursor:pointer}.shell{min-height:100vh;display:grid;grid-template-columns:252px minmax(0,1fr)}.sidebar{background:var(--navy);color:#dbe9e8;padding:29px 16px;display:flex;flex-direction:column;position:sticky;top:0;height:100vh}.brand{display:flex;align-items:center;gap:12px;padding:4px 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p{font-size:11px;color:#728588;line-height:1.55;margin:0 0 10px}.role small{font-size:10px;color:#3c7875}.review-layout{grid-template-columns:minmax(0,1fr) 280px;align-items:start;margin-bottom:20px}.review-layout aside{display:grid;gap:18px}.clinical-body h2{font:800 20px Manrope,sans-serif;margin:20px 0 8px}.clinical-body h3{font:800 16px Manrope,sans-serif;margin:20px 0 8px}.clinical-body p,.clinical-body li{color:#465f64;font-size:13px;line-height:1.75}.clinical-body ul{padding-left:22px}.source-link{display:block;overflow-wrap:anywhere;font-size:11px;margin:10px 0;border-top:1px solid var(--line);padding-top:10px}.note{border-top:1px solid var(--line);padding:12px 0}.note time{font-size:11px;color:#91a19f;margin-left:8px}.access-row{display:flex;justify-content:space-between;gap:10px;border-top:1px solid var(--line);padding:12px 0;align-items:center}.access-row strong,.access-row small{display:block}.access-row small{font-size:11px;color:#819394;margin-top:4px}.source-item{padding:15px 0;border-top:1px solid var(--line)}.source-item:first-child{border:0}.source-item strong{font-size:14px}.source-item small{display:block;font-size:11px;color:#8a9d9a;margin-top:4px}.source-item p{font-size:12px;color:#617b7d;max-width:900px}.audit-table{border-collapse:collapse;width:100%;font-size:12px;text-align:left}.audit-table th,.audit-table td{padding:10px;border-bottom:1px solid var(--line)}.narrow{max-width:680px}.auth-body{min-height:100vh;display:grid;place-items:center;background:linear-gradient(135deg,#102a35,#1b4e53)}.auth-card{width:min(430px,calc(100vw - 32px));background:#fff;border-radius:16px;padding:32px;box-shadow:0 30px 80px #09222a55}.auth-card .brand{margin:0 0 36px;padding:0}.auth-card .brand strong{color:var(--navy)}.auth-card h1{font:800 28px Manrope,sans-serif;margin:0 0 8px}.auth-card p{color:#778d8c}.auth-card label{margin:17px 0}.auth-card input{width:100%}.auth-card .muted{display:block;margin-top:15px;text-align:center}
@media(max-width:1120px){.metric-grid{grid-template-columns:repeat(2,1fr)}.roles-grid{grid-template-columns:repeat(2,1fr)}}@media(max-width:850px){.shell{grid-template-columns:minmax(0,1fr)}.sidebar{height:auto;position:static;padding:12px 15px;min-width:0}.sidebar .brand{margin:0 0 8px}.sidebar nav{flex-direction:row;overflow:auto;white-space:nowrap;min-width:0;max-width:100%}.sidebar nav a{padding:7px 11px}.sidebar nav hr,.side-foot{display:none}.topbar{padding:0 20px}.content{padding:28px 18px 60px}.two-column,.review-layout{grid-template-columns:1fr}.review-layout aside{grid-template-columns:repeat(2,1fr)}.calendar-grid{min-width:740px}.calendar-card{overflow-x:auto}}@media(max-width:570px){.top-actions .date-chip,.top-actions .user-chip{display:none}.page-intro{display:block}.page-intro .button,.page-actions{margin-top:16px}.metric-grid,.task-list,.roles-grid,.review-grid,.review-layout aside{grid-template-columns:1fr}.filter-form{flex-wrap:wrap}.filter-form select{min-width:0;flex:1}.status{white-space:normal}.doc-row .status{display:none}.slim-row{grid-template-columns:75px 1fr}.slim-row em{display:none}.task-update{flex-wrap:wrap}.task-update input{flex-basis:100%}.timeline-item{grid-template-columns:74px 12px 1fr;gap:8px}.panel{padding:19px}}